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Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children
AIM: Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a hepatic secretory protein which promotes the degradation of low-density lipoprotein receptors leading to reduced hepatic uptake of plasma cholesterol. Non-synonymous single-nucleotide polymorphisms in its gene have been linked to hypo-...
Autores principales: | Arama, Charles, Diarra, Issa, Kouriba, Bourèma, Sirois, Francine, Fedoryak, Olesya, Thera, Mahamadou A., Coulibaly, Drissa, Lyke, Kirsten E., Plowe, Christopher V., Chrétien, Michel, Doumbo, Ogobara K., Mbikay, Majambu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813955/ https://www.ncbi.nlm.nih.gov/pubmed/29447211 http://dx.doi.org/10.1371/journal.pone.0192850 |
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