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Kinetics of PTEN-mediated PI(3,4,5)P3 hydrolysis on solid supported membranes

Phosphatidylinositides play important roles in cellular signaling and migration. Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) is an important phosphatidylinositide because it acts as a secondary messenger to trigger cell movement and proliferation. A high level of PI(3,4,5)P3 at the plasma...

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Detalles Bibliográficos
Autores principales:	Liu, Chun, Deb, Sanghamitra, Ferreira, Vinicius S., Xu, Eric, Baumgart, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813967/ https://www.ncbi.nlm.nih.gov/pubmed/29447222 http://dx.doi.org/10.1371/journal.pone.0192667

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