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HIV epidemics in Shenzhen and Chongqing, China

OBJECTIVE: Men who have sex with men (MSM) and heterosexuals are the populations with the fastest growing HIV infection rates in China. We characterize the epidemic growth and age patterns between these two routes from 2004 to 2015 in Chongqing and Shenzhen, China. DESIGN AND METHODS: Data were down...

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Autores principales: Yang, Shu, Chiu, Alice P. Y., Lin, Qianying, Zeng, Ziqian, Li, Yafei, Zhang, Yao, Yang, Zhengrong, Yang, Lin, He, Daihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813969/
https://www.ncbi.nlm.nih.gov/pubmed/29447229
http://dx.doi.org/10.1371/journal.pone.0192849
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author Yang, Shu
Chiu, Alice P. Y.
Lin, Qianying
Zeng, Ziqian
Li, Yafei
Zhang, Yao
Yang, Zhengrong
Yang, Lin
He, Daihai
author_facet Yang, Shu
Chiu, Alice P. Y.
Lin, Qianying
Zeng, Ziqian
Li, Yafei
Zhang, Yao
Yang, Zhengrong
Yang, Lin
He, Daihai
author_sort Yang, Shu
collection PubMed
description OBJECTIVE: Men who have sex with men (MSM) and heterosexuals are the populations with the fastest growing HIV infection rates in China. We characterize the epidemic growth and age patterns between these two routes from 2004 to 2015 in Chongqing and Shenzhen, China. DESIGN AND METHODS: Data were downloaded from the National HIV/ AIDS Comprehensive Response Information Management System. For the new HIV diagnoses of heterosexuals and MSM in both cities, we estimated the growth rates by fitting different sub-exponential models. Heat maps are used to show their age patterns. We used histograms to compare these patterns by birth cohort. RESULTS: The MSM epidemics grew significantly in both cities. Chongqing experienced quadratic growth in HIV reported cases with an estimated growth rate of 0.086 per week and a “deceleration rate” of 0.673. HIV reported cases of MSM in Shenzhen grew even more drastically with a growth rate of 0.033 per week and “deceleration rate” of 0.794. The new infections are mainly affecting the ages of 18 to 30 in Chongqing and ages of 20 to 35 in Shenzhen. They peaked in early 1990’s and mid-1990’s birth cohorts in Chongqing and Shenzhen respectively. The HIV epidemic among heterosexuals grew rapidly in both cities. The growth rates were estimated as 0.02 and 0.028 in Chongqing and Shenzhen respectively whereas the “deceleration rates” were 0.878 and 0.790 in these two places. It affected mostly aged 18 to 75 in males and 18 to 65 in females in Chongqing and aged 18 to 45 in males and 18 to 50 in females in Shenzhen in 2015. In Chongqing, the heterosexual female epidemics display two peaks in HIV diagnoses in the birth cohorts of early 1950’s and early 1980’s, with heterosexual male epidemics peaked in early 1940’s and early 1960’s. The heterosexual male and female epidemics display higher rates in the birth cohort 1940-1960, than the birth cohort 1960-1990. It peaked in birth cohorts of 1950’s and 1980’s in Shenzhen. CONCLUSIONS: We revealed striking differences in epidemic growth and age patterns of the HIV epidemics in these two cities. Our results may be used to inform age-targeted public health policies to curb their epidemic growth.
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spelling pubmed-58139692018-03-02 HIV epidemics in Shenzhen and Chongqing, China Yang, Shu Chiu, Alice P. Y. Lin, Qianying Zeng, Ziqian Li, Yafei Zhang, Yao Yang, Zhengrong Yang, Lin He, Daihai PLoS One Research Article OBJECTIVE: Men who have sex with men (MSM) and heterosexuals are the populations with the fastest growing HIV infection rates in China. We characterize the epidemic growth and age patterns between these two routes from 2004 to 2015 in Chongqing and Shenzhen, China. DESIGN AND METHODS: Data were downloaded from the National HIV/ AIDS Comprehensive Response Information Management System. For the new HIV diagnoses of heterosexuals and MSM in both cities, we estimated the growth rates by fitting different sub-exponential models. Heat maps are used to show their age patterns. We used histograms to compare these patterns by birth cohort. RESULTS: The MSM epidemics grew significantly in both cities. Chongqing experienced quadratic growth in HIV reported cases with an estimated growth rate of 0.086 per week and a “deceleration rate” of 0.673. HIV reported cases of MSM in Shenzhen grew even more drastically with a growth rate of 0.033 per week and “deceleration rate” of 0.794. The new infections are mainly affecting the ages of 18 to 30 in Chongqing and ages of 20 to 35 in Shenzhen. They peaked in early 1990’s and mid-1990’s birth cohorts in Chongqing and Shenzhen respectively. The HIV epidemic among heterosexuals grew rapidly in both cities. The growth rates were estimated as 0.02 and 0.028 in Chongqing and Shenzhen respectively whereas the “deceleration rates” were 0.878 and 0.790 in these two places. It affected mostly aged 18 to 75 in males and 18 to 65 in females in Chongqing and aged 18 to 45 in males and 18 to 50 in females in Shenzhen in 2015. In Chongqing, the heterosexual female epidemics display two peaks in HIV diagnoses in the birth cohorts of early 1950’s and early 1980’s, with heterosexual male epidemics peaked in early 1940’s and early 1960’s. The heterosexual male and female epidemics display higher rates in the birth cohort 1940-1960, than the birth cohort 1960-1990. It peaked in birth cohorts of 1950’s and 1980’s in Shenzhen. CONCLUSIONS: We revealed striking differences in epidemic growth and age patterns of the HIV epidemics in these two cities. Our results may be used to inform age-targeted public health policies to curb their epidemic growth. Public Library of Science 2018-02-15 /pmc/articles/PMC5813969/ /pubmed/29447229 http://dx.doi.org/10.1371/journal.pone.0192849 Text en © 2018 Yang et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Yang, Shu
Chiu, Alice P. Y.
Lin, Qianying
Zeng, Ziqian
Li, Yafei
Zhang, Yao
Yang, Zhengrong
Yang, Lin
He, Daihai
HIV epidemics in Shenzhen and Chongqing, China
title HIV epidemics in Shenzhen and Chongqing, China
title_full HIV epidemics in Shenzhen and Chongqing, China
title_fullStr HIV epidemics in Shenzhen and Chongqing, China
title_full_unstemmed HIV epidemics in Shenzhen and Chongqing, China
title_short HIV epidemics in Shenzhen and Chongqing, China
title_sort hiv epidemics in shenzhen and chongqing, china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813969/
https://www.ncbi.nlm.nih.gov/pubmed/29447229
http://dx.doi.org/10.1371/journal.pone.0192849
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