Interferon sensitivity-determining region of hepatitis C virus influences virus production and interferon signaling

The number of amino acid substitutions in the interferon (IFN) sensitivity-determining region (ISDR) of hepatitis C virus (HCV) NS5A is a strong predictor for the outcome of IFN-based treatment. To assess the involvement of ISDR in the HCV life cycle and to clarify the molecular mechanisms influenci...

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Detalles Bibliográficos
Autores principales: Sugiyama, Ryuichi, Murayama, Asako, Nitta, Sayuri, Yamada, Norie, Tasaka-Fujita, Megumi, Masaki, Takahiro, Aly, Hussein Hassan, Shiina, Masaaki, Ryo, Akihide, Ishii, Koji, Wakita, Takaji, Kato, Takanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814163/
https://www.ncbi.nlm.nih.gov/pubmed/29464023
http://dx.doi.org/10.18632/oncotarget.23562

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