Cargando…
YAP-associated chromosomal instability and cholangiocarcinoma in mice
Deregulated Hippo pathway signaling is associated with aberrant activation of the downstream effector yes-associated protein (YAP), an emerging key oncogenic mediator in cholangiocarcinoma (CCA). In our prior work, we have demonstrated that biliary transduction of YAP along with Akt as a permissive...
Autores principales: | Rizvi, Sumera, Fischbach, Samantha R., Bronk, Steven F., Hirsova, Petra, Krishnan, Anuradha, Dhanasekaran, Renumathy, Smadbeck, James B., Smoot, Rory L., Vasmatzis, George, Gores, Gregory J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814182/ https://www.ncbi.nlm.nih.gov/pubmed/29464042 http://dx.doi.org/10.18632/oncotarget.23638 |
Ejemplares similares
-
YAP and the Hippo pathway in cholangiocarcinoma
por: Sugihara, Takaaki, et al.
Publicado: (2019) -
Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice
por: Guicciardi, Maria Eugenia, et al.
Publicado: (2017) -
Immunobiology of cholangiocarcinoma
por: Loeuillard, Emilien, et al.
Publicado: (2019) -
Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma
por: Tóth, Marcell, et al.
Publicado: (2021) -
Vismodegib Suppresses TRAIL-mediated Liver Injury in a Mouse Model of Nonalcoholic Steatohepatitis
por: Hirsova, Petra, et al.
Publicado: (2013)