Cargando…

Inhibition of IAP’s and activation of p53 leads to caspase-dependent apoptosis in gastric cancer cells treated with Scutellarein

Gastric cancer is the fifth most common cancer and the third leading cause of cancer deaths worldwide. South Korea is in first place with 9,180 death alone attributed to gastric cancer in 2013. Plenty of literature suggests the evasion of apoptosis is implicated in neurodegeneration, autoimmune dise...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gowda Saralamma, Venu Venkatarame, Lee, Ho Jeong, Raha, Suchismita, Lee, Won Sup, Kim, Eun Hee, Lee, Sang Joon, Heo, Jeong Doo, Won, Chungkil, Kang, Chang Keun, Kim, Gon Sup
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814189/ https://www.ncbi.nlm.nih.gov/pubmed/29464049 http://dx.doi.org/10.18632/oncotarget.23202

Ejemplares similares

Comparative proteomic analysis uncovers potential biomarkers involved in the anticancer effect of Scutellarein in human gastric cancer cells
por: Saralamma, Venu Venkatarame Gowda, et al.
Publicado: (2020)

Scutellarein Induces Fas-Mediated Extrinsic Apoptosis and G2/M Cell Cycle Arrest in Hep3B Hepatocellular Carcinoma Cells
por: Ha, Sang Eun, et al.
Publicado: (2019)

Proteomic profiling of human HepG2 cells treated with hesperidin using antibody array
por: Yumnam, Silvia, et al.
Publicado: (2017)

Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway
por: Lee, Ho Jeong, et al.
Publicado: (2018)

Poncirin Induces Apoptosis in AGS Human Gastric Cancer Cells through Extrinsic Apoptotic Pathway by up-Regulation of Fas Ligand
por: Venkatarame Gowda Saralamma, Venu, et al.
Publicado: (2015)

Identification of a novel biomarker in tangeretin-induced cell death in AGS human gastric cancer cells
por: Yumnam, Silvia, et al.
Publicado: (2018)

Korean Scutellaria baicalensis Georgi flavonoid extract induces mitochondrially mediated apoptosis in human gastric cancer AGS cells
por: Venkatarame Gowda Saralamma, Venu, et al.
Publicado: (2017)

Essential oil from Korean Chamaecyparis obtusa leaf ameliorates respiratory activity in Sprague-Dawley rats and exhibits protection from NF-κB-induced inflammation in WI38 fibroblast cells
por: Raha, Suchismita, et al.
Publicado: (2019)

Flavonoids isolated from Citrus platymamma induced G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells
por: Nagappan, Arulkumar, et al.
Publicado: (2016)

Sinensetin Induces Autophagic Cell Death through p53-Related AMPK/mTOR Signaling in Hepatocellular Carcinoma HepG2 Cells
por: Kim, Seong Min, et al.
Publicado: (2020)

Comparative Proteomic Profiling of Tumor-Associated Proteins in Human Gastric Cancer Cells Treated with Pectolinarigenin
por: Lee, Ho Jeong, et al.
Publicado: (2018)

Proteome profiling of lipopolysaccharide induced L6 rat skeletal muscle cells response to flavonoids from Scutellaria baicalensis Georgi
por: Kim, Jin A, et al.
Publicado: (2014)

Proteome Profiling of Membrane-Free Stem Cell Components by Nano-LS/MS Analysis and Its Anti-Inflammatory Activity
por: Venkatarame Gowda Saralamma, Venu, et al.
Publicado: (2019)

Membrane-Free Stem Cell Components Inhibit Interleukin-1α-Stimulated Inflammation and Cartilage Degradation In Vitro and In Vivo: A Rat Model of Osteoarthritis
por: Lee, Ho Jeong, et al.
Publicado: (2019)

Artemisia iwayomogi (Dowijigi) inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppressing the NF-κB signaling pathway
por: Kim, Seong Min, et al.
Publicado: (2020)

Inhibition of Cell Proliferation and Metastasis by Scutellarein Regulating PI3K/Akt/NF-κB Signaling through PTEN Activation in Hepatocellular Carcinoma
por: Ha, Sang Eun, et al.
Publicado: (2021)

Scutellarein Inhibits LPS-Induced Inflammation through NF-κB/MAPKs Signaling Pathway in RAW264.7 Cells
por: Park, Min Yeong, et al.
Publicado: (2022)

Polyphenol mixture of a native Korean variety of Artemisia argyi H. (Seomae mugwort) and its anti-inflammatory effects
por: Kim, Seong Min, et al.
Publicado: (2019)

Sinensetin regulates age-related sarcopenia in cultured primary thigh and calf muscle cells
por: Kim, Jin-A, et al.
Publicado: (2019)

Polyphenolic compounds from Korean Lonicera japonica Thunb. induces apoptosis via AKT and caspase cascade activation in A549 cells
por: Park, Kwang Il, et al.
Publicado: (2017)

Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13
por: Yu, Mi-Sun, et al.
Publicado: (2012)

β-Lapachone Exerts Anticancer Effects by Downregulating p53, Lys-Acetylated Proteins, TrkA, p38 MAPK, SOD1, Caspase-2, CD44 and NPM in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells
por: Jung, Eun Joo, et al.
Publicado: (2023)

Tetraarsenic Hexoxide Induces Beclin-1-Induced Autophagic Cell Death as well as Caspase-Dependent Apoptosis in U937 Human Leukemic Cells
por: Han, Min Ho, et al.
Publicado: (2012)

Quantitative Proteomics Analysis for the Identification of Differential Protein Expression in Calf Muscles between Young and Old SD Rats Using Mass Spectrometry
por: Kim, Jin A., et al.
Publicado: (2021)

Development of machine learning models for the screening of potential HSP90 inhibitors
por: Khan, Mohd Imran, et al.
Publicado: (2022)

Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative
por: Gu, Ting, et al.
Publicado: (2017)

Scutellarein Reduces Inflammatory Responses by Inhibiting Src Kinase Activity
por: Sung, Nak Yoon, et al.
Publicado: (2015)

Antiproliferative Action of Conjugated Linoleic Acid on Human MCF-7 Breast Cancer Cells Mediated by Enhancement of Gap Junctional Intercellular Communication through Inactivation of NF-κB
por: Rakib, Md. Abdur, et al.
Publicado: (2013)

Pretreatment of Anthocyanin from the Fruit of Vitis coignetiae Pulliat Acts as a Potent Inhibitor of TNF-α Effect by Inhibiting NF-κB-Regulated Genes in Human Breast Cancer Cells
por: Paramanantham, Anjugam, et al.
Publicado: (2020)

p53 Enhances Artemisia annua L. Polyphenols-Induced Cell Death Through Upregulation of p53-Dependent Targets and Cleavage of PARP1 and Lamin A/C in HCT116 Colorectal Cancer Cells
por: Jung, Eun Joo, et al.
Publicado: (2020)

An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin
por: Dong, Ze-Xi, et al.
Publicado: (2016)

Application of therapeutic plasma exchange in patients having severe fever with thrombocytopenia syndrome
por: Yoo, Jeong Rae, et al.
Publicado: (2019)

Iridin Induces G2/M Phase Cell Cycle Arrest and Extrinsic Apoptotic Cell Death through PI3K/AKT Signaling Pathway in AGS Gastric Cancer Cells
por: Bhosale, Pritam-Bhagwan, et al.
Publicado: (2021)

Structural Insights and Development of LRRK2 Inhibitors for Parkinson’s Disease in the Last Decade
por: Thakur, Gunjan, et al.
Publicado: (2022)

Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells
por: Nagappan, Arulkumar, et al.
Publicado: (2017)

A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer
por: Moon, Jai-Hee, et al.
Publicado: (2015)

Polyphenols Isolated from Allium cepa L. Induces Apoptosis by Induction of p53 and Suppression of Bcl-2 through Inhibiting PI3K/Akt Signaling Pathway in AGS Human Cancer Cells
por: Lee, Won Sup, et al.
Publicado: (2014)

Anthocyanins from Vitis coignetiae Pulliat Inhibit Cancer Invasion and Epithelial-Mesenchymal Transition, but These Effects Can Be Attenuated by Tumor Necrosis Factor in Human Uterine Cervical Cancer HeLa Cells
por: Lu, Jing Nan, et al.
Publicado: (2013)

Drosophila IAP1-Mediated Ubiquitylation Controls Activation of the Initiator Caspase DRONC Independent of Protein Degradation
por: Lee, Tom V., et al.
Publicado: (2011)

Cellular Regulation of Kynurenic Acid-Induced Cell Apoptosis Pathways in AGS Cells
por: Kim, Hun Hwan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rdrr5c1m0v58lr1nd36n5e94n3