Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease

Mitochondrial dynamics, involving a balance between fusion and fission, regulates mitochondrial quality and number. Increasing evidence suggests that dysfunctional mitochondria play a role in Alzheimer's disease (AD). We observed that Drp1 interaction with one of the adaptors, Fis1, is signific...

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Detalles Bibliográficos
Autores principales: Joshi, Amit U., Saw, Nay L., Shamloo, Mehrdad, Mochly-Rosen, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814200/
https://www.ncbi.nlm.nih.gov/pubmed/29464060
http://dx.doi.org/10.18632/oncotarget.23640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814200/
https://www.ncbi.nlm.nih.gov/pubmed/29464060
http://dx.doi.org/10.18632/oncotarget.23640

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