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Effects of a small molecule R-spondin-1 substitute RS-246204 on a mouse intestinal organoid culture
Organoids, a multi-cellular and organ-like structure cultured in vitro, can be used in a variety of fields such as disease modeling, drug discovery, or cell therapy development. When organoids derived from Lgr5 stem cells are cultured ex vivo, recombinant R-spondin-1 protein should be added at a hig...
Autores principales: | Nam, Myeong-Ok, Hahn, Soojung, Jee, Joo Hyun, Hwang, Tae-Sun, Yoon, Ho, Lee, Dong Hyeon, Kwon, Min-Soo, Yoo, Jongman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814218/ https://www.ncbi.nlm.nih.gov/pubmed/29464078 http://dx.doi.org/10.18632/oncotarget.23721 |
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