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Differential tumor biological role of the tumor suppressor KAI1 and its splice variant in human breast cancer cells

The tetraspanin and tumor suppressor KAI1 is downregulated or lost in many cancers which correlates with poor prognosis. KAI1 acts via physical/functional crosstalk with other membrane receptors. Also, a splice variant of KAI1 (KAI1-SP) has been identified indicative of poor prognosis. We here chara...

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Detalles Bibliográficos
Autores principales: Miller, Julia, Dreyer, Tobias F., Bächer, Anne Sophie, Sinner, Eva-Kathrin, Heinrich, Christine, Benge, Anke, Gross, Eva, Preis, Sarah, Rother, Jan, Roberts, Anthony, Nelles, Gabriele, Miteva, Tzenka, Reuning, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814219/
https://www.ncbi.nlm.nih.gov/pubmed/29464079
http://dx.doi.org/10.18632/oncotarget.23968

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