c-Maf-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont

Both microbial and host genetic factors contribute to the pathogenesis of autoimmune disease(1–4). Accumulating evidence suggests that microbial species that potentiate chronic inflammation, as in inflammatory bowel disease (IBD), often also colonize healthy individuals. These microbes, including th...

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Detalles Bibliográficos
Autores principales: Xu, Mo, Pokrovskii, Maria, Ding, Yi, Yi, Ren, Au, Christy, Harrison, Oliver J., Galan, Carolina, Belkaid, Yasmine, Bonneau, Richard, Littman, Dan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814346/
https://www.ncbi.nlm.nih.gov/pubmed/29414937
http://dx.doi.org/10.1038/nature25500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814346/
https://www.ncbi.nlm.nih.gov/pubmed/29414937
http://dx.doi.org/10.1038/nature25500

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