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c-Maf-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont
Both microbial and host genetic factors contribute to the pathogenesis of autoimmune disease(1–4). Accumulating evidence suggests that microbial species that potentiate chronic inflammation, as in inflammatory bowel disease (IBD), often also colonize healthy individuals. These microbes, including th...
Autores principales: | Xu, Mo, Pokrovskii, Maria, Ding, Yi, Yi, Ren, Au, Christy, Harrison, Oliver J., Galan, Carolina, Belkaid, Yasmine, Bonneau, Richard, Littman, Dan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814346/ https://www.ncbi.nlm.nih.gov/pubmed/29414937 http://dx.doi.org/10.1038/nature25500 |
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