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Substructure-activity relationship studies on antibody recognition for phenylurea compounds using competitive immunoassay and computational chemistry
Based on the structural features of fluometuron, an immunizing hapten was synthesized and conjugated to bovine serum albumin as an immunogen to prepare a polyclonal antibody. However, the resultant antibody indicated cross-reactivity with 6 structurally similar phenylurea herbicides, with binding ac...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814414/ https://www.ncbi.nlm.nih.gov/pubmed/29449597 http://dx.doi.org/10.1038/s41598-018-21394-x |