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Substructure-activity relationship studies on antibody recognition for phenylurea compounds using competitive immunoassay and computational chemistry

Based on the structural features of fluometuron, an immunizing hapten was synthesized and conjugated to bovine serum albumin as an immunogen to prepare a polyclonal antibody. However, the resultant antibody indicated cross-reactivity with 6 structurally similar phenylurea herbicides, with binding ac...

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Detalles Bibliográficos
Autores principales: Zhang, Fuyuan, Liu, Bing, Liu, Guozhen, Zhang, Yan, Wang, Junping, Wang, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814414/
https://www.ncbi.nlm.nih.gov/pubmed/29449597
http://dx.doi.org/10.1038/s41598-018-21394-x