Cargando…
Protection from experimental cerebral malaria with a single intravenous or subcutaneous whole-parasite immunization
Cerebral malaria is a life-threatening complication of Plasmodia infection and a major cause of child mortality in Sub-Saharan Africa. We report that protection from experimental cerebral malaria in the rodent model is obtained by a single intravenous or subcutaneous whole-parasite immunization. Who...
Autores principales: | Heiss, Kirsten, Maier, Marion Irmgard, Hoffmann, Angelika, Frank, Roland, Bendszus, Martin, Mueller, Ann-Kristin, Pfeil, Johannes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814423/ https://www.ncbi.nlm.nih.gov/pubmed/29449638 http://dx.doi.org/10.1038/s41598-018-21551-2 |
Ejemplares similares
-
Addition of histamine to subcutaneously injected Plasmodium berghei sporozoites increases the parasite liver load and could facilitate whole-parasite vaccination
por: Pfeil, Johannes, et al.
Publicado: (2015) -
Experimental Cerebral Malaria Spreads along the Rostral Migratory Stream
por: Hoffmann, Angelika, et al.
Publicado: (2016) -
A Plasmodium Cross-Stage Antigen Contributes to the Development of Experimental Cerebral Malaria
por: Fernandes, Priyanka, et al.
Publicado: (2018) -
CD8(+) T Cells Mediate Robust Stage-Specific Immunity to P. berghei under Chemoprophylaxis and This Protective Environment Is Not Downregulated by the Presence of Blood-Stage Infection
por: Lewis, Matthew D., et al.
Publicado: (2014) -
Protective efficacy and safety of liver stage attenuated malaria parasites
por: Kumar, Hirdesh, et al.
Publicado: (2016)