Heparan sulfates facilitate harmless amyloidogenic fibril formation interacting with elastin-like peptides

Heparan sulfates (HSs) modulate tissue elasticity in physiopathological conditions by interacting with various matrix constituents as tropoelastin and elastin-derived peptides. HSs bind also to protein moieties accelerating amyloid formation and influencing cytotoxic properties of insoluble fibrils....

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Detalles Bibliográficos
Autores principales: Boraldi, Federica, Moscarelli, Pasquale, Bochicchio, Brigida, Pepe, Antonietta, Salvi, Anna M., Quaglino, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814424/
https://www.ncbi.nlm.nih.gov/pubmed/29449596
http://dx.doi.org/10.1038/s41598-018-21472-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814424/
https://www.ncbi.nlm.nih.gov/pubmed/29449596
http://dx.doi.org/10.1038/s41598-018-21472-0

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