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Heparan sulfates facilitate harmless amyloidogenic fibril formation interacting with elastin-like peptides
Heparan sulfates (HSs) modulate tissue elasticity in physiopathological conditions by interacting with various matrix constituents as tropoelastin and elastin-derived peptides. HSs bind also to protein moieties accelerating amyloid formation and influencing cytotoxic properties of insoluble fibrils....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814424/ https://www.ncbi.nlm.nih.gov/pubmed/29449596 http://dx.doi.org/10.1038/s41598-018-21472-0 |