Dynamic allocation of orthogonal ribosomes facilitates uncoupling of co-expressed genes

Introduction of synthetic circuits into microbes creates competition between circuit and host genes for shared cellular resources, such as ribosomes. This can lead to the emergence of unwanted coupling between the expression of different circuit genes, complicating the design process and potentially...

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Detalles Bibliográficos
Autores principales: Darlington, Alexander P. S., Kim, Juhyun, Jiménez, José I., Bates, Declan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814443/
https://www.ncbi.nlm.nih.gov/pubmed/29449554
http://dx.doi.org/10.1038/s41467-018-02898-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814443/
https://www.ncbi.nlm.nih.gov/pubmed/29449554
http://dx.doi.org/10.1038/s41467-018-02898-6

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