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Dynamic allocation of orthogonal ribosomes facilitates uncoupling of co-expressed genes
Introduction of synthetic circuits into microbes creates competition between circuit and host genes for shared cellular resources, such as ribosomes. This can lead to the emergence of unwanted coupling between the expression of different circuit genes, complicating the design process and potentially...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814443/ https://www.ncbi.nlm.nih.gov/pubmed/29449554 http://dx.doi.org/10.1038/s41467-018-02898-6 |