Chronic ET(A) antagonist reverses hypertension and impairment of structure and function of peripheral small arteries in aortic stiffening

Arterial stiffness may contribute to the pathogenesis of hypertension. The goal of this study is to elucidate the role of Endothelin-1 (ET-1) in aortic stiffening-induced hypertension through ET(A) receptor activation. An increase in aortic stiffness was created by use of a non-constrictive restrain...

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Detalles Bibliográficos
Autores principales: Guo, Xiaomei, Chen, Huan, Han, Ling, Haulon, Stephan, Kassab, Ghassan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814460/
https://www.ncbi.nlm.nih.gov/pubmed/29449619
http://dx.doi.org/10.1038/s41598-018-20439-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814460/
https://www.ncbi.nlm.nih.gov/pubmed/29449619
http://dx.doi.org/10.1038/s41598-018-20439-5

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