A community approach to mortality prediction in sepsis via gene expression analysis

Improved risk stratification and prognosis prediction in sepsis is a critical unmet need. Clinical severity scores and available assays such as blood lactate reflect global illness severity with suboptimal performance, and do not specifically reveal the underlying dysregulation of sepsis. Here, we p...

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Detalles Bibliográficos
Autores principales: Sweeney, Timothy E., Perumal, Thanneer M., Henao, Ricardo, Nichols, Marshall, Howrylak, Judith A., Choi, Augustine M., Bermejo-Martin, Jesús F., Almansa, Raquel, Tamayo, Eduardo, Davenport, Emma E., Burnham, Katie L., Hinds, Charles J., Knight, Julian C., Woods, Christopher W., Kingsmore, Stephen F., Ginsburg, Geoffrey S., Wong, Hector R., Parnell, Grant P., Tang, Benjamin, Moldawer, Lyle L., Moore, Frederick E., Omberg, Larsson, Khatri, Purvesh, Tsalik, Ephraim L., Mangravite, Lara M., Langley, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814463/
https://www.ncbi.nlm.nih.gov/pubmed/29449546
http://dx.doi.org/10.1038/s41467-018-03078-2

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