New virus of the family Flaviviridae detected in lumpfish (Cyclopterus lumpus)

In this study, we determined the complete coding sequence of a putative new member of the family Flaviviridae, named “Cyclopterus lumpus virus” (CLuV), which is associated with a serious disease in lumpfish (Cyclopterus lumpus). The virus was present in all tissues tested, but pathology was primaril...

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Detalles Bibliográficos
Autores principales: Skoge, Renate Hvidsten, Brattespe, Jarle, Økland, Arnfinn Lodden, Plarre, Heidrun, Nylund, Are
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814470/
https://www.ncbi.nlm.nih.gov/pubmed/29147783
http://dx.doi.org/10.1007/s00705-017-3643-3
Descripción
Sumario:In this study, we determined the complete coding sequence of a putative new member of the family Flaviviridae, named “Cyclopterus lumpus virus” (CLuV), which is associated with a serious disease in lumpfish (Cyclopterus lumpus). The virus was present in all tissues tested, but pathology was primarily observed in the liver and kidneys. CLuV shows low but distinct similarity to the unassigned Tamana bat virus (TABV). Unlike other known members of the family Flaviviridae, translation of the entire CLuV polyprotein is dependent on a − 1 ribosomal frameshift in the NS2A region.

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