New virus of the family Flaviviridae detected in lumpfish (Cyclopterus lumpus)

In this study, we determined the complete coding sequence of a putative new member of the family Flaviviridae, named “Cyclopterus lumpus virus” (CLuV), which is associated with a serious disease in lumpfish (Cyclopterus lumpus). The virus was present in all tissues tested, but pathology was primaril...

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Autores principales: Skoge, Renate Hvidsten, Brattespe, Jarle, Økland, Arnfinn Lodden, Plarre, Heidrun, Nylund, Are
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814470/
https://www.ncbi.nlm.nih.gov/pubmed/29147783
http://dx.doi.org/10.1007/s00705-017-3643-3
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author Skoge, Renate Hvidsten
Brattespe, Jarle
Økland, Arnfinn Lodden
Plarre, Heidrun
Nylund, Are
author_facet Skoge, Renate Hvidsten
Brattespe, Jarle
Økland, Arnfinn Lodden
Plarre, Heidrun
Nylund, Are
author_sort Skoge, Renate Hvidsten
collection PubMed
description In this study, we determined the complete coding sequence of a putative new member of the family Flaviviridae, named “Cyclopterus lumpus virus” (CLuV), which is associated with a serious disease in lumpfish (Cyclopterus lumpus). The virus was present in all tissues tested, but pathology was primarily observed in the liver and kidneys. CLuV shows low but distinct similarity to the unassigned Tamana bat virus (TABV). Unlike other known members of the family Flaviviridae, translation of the entire CLuV polyprotein is dependent on a − 1 ribosomal frameshift in the NS2A region.
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spelling pubmed-58144702018-02-26 New virus of the family Flaviviridae detected in lumpfish (Cyclopterus lumpus) Skoge, Renate Hvidsten Brattespe, Jarle Økland, Arnfinn Lodden Plarre, Heidrun Nylund, Are Arch Virol Brief Report In this study, we determined the complete coding sequence of a putative new member of the family Flaviviridae, named “Cyclopterus lumpus virus” (CLuV), which is associated with a serious disease in lumpfish (Cyclopterus lumpus). The virus was present in all tissues tested, but pathology was primarily observed in the liver and kidneys. CLuV shows low but distinct similarity to the unassigned Tamana bat virus (TABV). Unlike other known members of the family Flaviviridae, translation of the entire CLuV polyprotein is dependent on a − 1 ribosomal frameshift in the NS2A region. Springer Vienna 2017-11-17 2018 /pmc/articles/PMC5814470/ /pubmed/29147783 http://dx.doi.org/10.1007/s00705-017-3643-3 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Brief Report
Skoge, Renate Hvidsten
Brattespe, Jarle
Økland, Arnfinn Lodden
Plarre, Heidrun
Nylund, Are
New virus of the family Flaviviridae detected in lumpfish (Cyclopterus lumpus)
title New virus of the family Flaviviridae detected in lumpfish (Cyclopterus lumpus)
title_full New virus of the family Flaviviridae detected in lumpfish (Cyclopterus lumpus)
title_fullStr New virus of the family Flaviviridae detected in lumpfish (Cyclopterus lumpus)
title_full_unstemmed New virus of the family Flaviviridae detected in lumpfish (Cyclopterus lumpus)
title_short New virus of the family Flaviviridae detected in lumpfish (Cyclopterus lumpus)
title_sort new virus of the family flaviviridae detected in lumpfish (cyclopterus lumpus)
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814470/
https://www.ncbi.nlm.nih.gov/pubmed/29147783
http://dx.doi.org/10.1007/s00705-017-3643-3
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