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Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse
There is no therapeutic intervention proven to prevent acute respiratory distress syndrome (ARDS). Novel mechanistic insights into the pathophysiology of ARDS are therefore required. Platelets are implicated in regulating many of the pathogenic processes that occur during ARDS; however, the mechanis...
Autores principales: | Lax, Siân, Rayes, Julie, Wichaiyo, Surasak, Haining, Elizabeth J., Lowe, Kate, Grygielska, Beata, Laloo, Ryan, Flodby, Per, Borok, Zea, Crandall, Edward D., Thickett, David R., Watson, Steve P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814702/ https://www.ncbi.nlm.nih.gov/pubmed/28839100 http://dx.doi.org/10.1152/ajplung.00023.2017 |
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