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Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse

There is no therapeutic intervention proven to prevent acute respiratory distress syndrome (ARDS). Novel mechanistic insights into the pathophysiology of ARDS are therefore required. Platelets are implicated in regulating many of the pathogenic processes that occur during ARDS; however, the mechanis...

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Detalles Bibliográficos
Autores principales: Lax, Siân, Rayes, Julie, Wichaiyo, Surasak, Haining, Elizabeth J., Lowe, Kate, Grygielska, Beata, Laloo, Ryan, Flodby, Per, Borok, Zea, Crandall, Edward D., Thickett, David R., Watson, Steve P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814702/
https://www.ncbi.nlm.nih.gov/pubmed/28839100
http://dx.doi.org/10.1152/ajplung.00023.2017

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