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Lipid‐DNAs as Solubilizers of mTHPC
Hydrophobic drug candidates require innovative formulation agents. We designed and synthesized lipid‐DNA polymers containing varying numbers of hydrophobic alkyl chains. The hydrophobicity of these amphiphiles is easily tunable by introducing a defined number of alkyl chain‐modified nucleotides duri...
Autores principales: | Liu, Yun, de Vries, Jan Willem, Liu, Qing, Hartman, Alwin M., Wieland, Gerhard D., Wieczorek, Sebastian, Börner, Hans G., Wiehe, Arno, Buhler, Eric, Stuart, Marc C. A., Browne, Wesley R., Herrmann, Andreas, Hirsch, Anna K. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814723/ https://www.ncbi.nlm.nih.gov/pubmed/29194834 http://dx.doi.org/10.1002/chem.201705206 |
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