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Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants
Plant growth flexibly adapts to environmental conditions, implying cross‐talk between environmental signalling and developmental regulation. Here, we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen‐activated protein kinase (MAPK) sites adjacent to the...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814726/ https://www.ncbi.nlm.nih.gov/pubmed/29197077 http://dx.doi.org/10.1002/1873-3468.12929 |
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author | Dory, Magdalena Hatzimasoura, Elizabeth Kállai, Brigitta M. Nagy, Szilvia K. Jäger, Katalin Darula, Zsuzsanna Nádai, Tímea V. Mészáros, Tamás López‐Juez, Enrique Barnabás, Beáta Palme, Klaus Bögre, László Ditengou, Franck A. Dóczi, Róbert |
author_facet | Dory, Magdalena Hatzimasoura, Elizabeth Kállai, Brigitta M. Nagy, Szilvia K. Jäger, Katalin Darula, Zsuzsanna Nádai, Tímea V. Mészáros, Tamás López‐Juez, Enrique Barnabás, Beáta Palme, Klaus Bögre, László Ditengou, Franck A. Dóczi, Róbert |
author_sort | Dory, Magdalena |
collection | PubMed |
description | Plant growth flexibly adapts to environmental conditions, implying cross‐talk between environmental signalling and developmental regulation. Here, we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen‐activated protein kinase (MAPK) sites adjacent to the phosphorylation sites of the well‐characterised AGC kinase PINOID, which regulates the polar localisation of PINs and directional auxin transport, thereby underpinning organ growth. The conserved sites of PIN1 are phosphorylated in vitro by two environmentally activated MAPKs, MPK4 and MPK6. In contrast to AGC kinases, MAPK‐mediated phosphorylation of PIN1 at adjacent sites leads to a partial loss of the plasma membrane localisation of PIN1. MAPK‐mediated modulation of PIN trafficking may participate in environmental adjustment of plant growth. |
format | Online Article Text |
id | pubmed-5814726 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-58147262018-02-21 Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants Dory, Magdalena Hatzimasoura, Elizabeth Kállai, Brigitta M. Nagy, Szilvia K. Jäger, Katalin Darula, Zsuzsanna Nádai, Tímea V. Mészáros, Tamás López‐Juez, Enrique Barnabás, Beáta Palme, Klaus Bögre, László Ditengou, Franck A. Dóczi, Róbert FEBS Lett Research Letters Plant growth flexibly adapts to environmental conditions, implying cross‐talk between environmental signalling and developmental regulation. Here, we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen‐activated protein kinase (MAPK) sites adjacent to the phosphorylation sites of the well‐characterised AGC kinase PINOID, which regulates the polar localisation of PINs and directional auxin transport, thereby underpinning organ growth. The conserved sites of PIN1 are phosphorylated in vitro by two environmentally activated MAPKs, MPK4 and MPK6. In contrast to AGC kinases, MAPK‐mediated phosphorylation of PIN1 at adjacent sites leads to a partial loss of the plasma membrane localisation of PIN1. MAPK‐mediated modulation of PIN trafficking may participate in environmental adjustment of plant growth. John Wiley and Sons Inc. 2017-12-25 2018-01 /pmc/articles/PMC5814726/ /pubmed/29197077 http://dx.doi.org/10.1002/1873-3468.12929 Text en © 2017 The Authors. FEBS Letters published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Letters Dory, Magdalena Hatzimasoura, Elizabeth Kállai, Brigitta M. Nagy, Szilvia K. Jäger, Katalin Darula, Zsuzsanna Nádai, Tímea V. Mészáros, Tamás López‐Juez, Enrique Barnabás, Beáta Palme, Klaus Bögre, László Ditengou, Franck A. Dóczi, Róbert Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants |
title | Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants |
title_full | Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants |
title_fullStr | Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants |
title_full_unstemmed | Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants |
title_short | Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants |
title_sort | coevolving mapk and pid phosphosites indicate an ancient environmental control of pin auxin transporters in land plants |
topic | Research Letters |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814726/ https://www.ncbi.nlm.nih.gov/pubmed/29197077 http://dx.doi.org/10.1002/1873-3468.12929 |
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