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Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants

Plant growth flexibly adapts to environmental conditions, implying cross‐talk between environmental signalling and developmental regulation. Here, we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen‐activated protein kinase (MAPK) sites adjacent to the...

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Autores principales: Dory, Magdalena, Hatzimasoura, Elizabeth, Kállai, Brigitta M., Nagy, Szilvia K., Jäger, Katalin, Darula, Zsuzsanna, Nádai, Tímea V., Mészáros, Tamás, López‐Juez, Enrique, Barnabás, Beáta, Palme, Klaus, Bögre, László, Ditengou, Franck A., Dóczi, Róbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814726/
https://www.ncbi.nlm.nih.gov/pubmed/29197077
http://dx.doi.org/10.1002/1873-3468.12929
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author Dory, Magdalena
Hatzimasoura, Elizabeth
Kállai, Brigitta M.
Nagy, Szilvia K.
Jäger, Katalin
Darula, Zsuzsanna
Nádai, Tímea V.
Mészáros, Tamás
López‐Juez, Enrique
Barnabás, Beáta
Palme, Klaus
Bögre, László
Ditengou, Franck A.
Dóczi, Róbert
author_facet Dory, Magdalena
Hatzimasoura, Elizabeth
Kállai, Brigitta M.
Nagy, Szilvia K.
Jäger, Katalin
Darula, Zsuzsanna
Nádai, Tímea V.
Mészáros, Tamás
López‐Juez, Enrique
Barnabás, Beáta
Palme, Klaus
Bögre, László
Ditengou, Franck A.
Dóczi, Róbert
author_sort Dory, Magdalena
collection PubMed
description Plant growth flexibly adapts to environmental conditions, implying cross‐talk between environmental signalling and developmental regulation. Here, we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen‐activated protein kinase (MAPK) sites adjacent to the phosphorylation sites of the well‐characterised AGC kinase PINOID, which regulates the polar localisation of PINs and directional auxin transport, thereby underpinning organ growth. The conserved sites of PIN1 are phosphorylated in vitro by two environmentally activated MAPKs, MPK4 and MPK6. In contrast to AGC kinases, MAPK‐mediated phosphorylation of PIN1 at adjacent sites leads to a partial loss of the plasma membrane localisation of PIN1. MAPK‐mediated modulation of PIN trafficking may participate in environmental adjustment of plant growth.
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spelling pubmed-58147262018-02-21 Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants Dory, Magdalena Hatzimasoura, Elizabeth Kállai, Brigitta M. Nagy, Szilvia K. Jäger, Katalin Darula, Zsuzsanna Nádai, Tímea V. Mészáros, Tamás López‐Juez, Enrique Barnabás, Beáta Palme, Klaus Bögre, László Ditengou, Franck A. Dóczi, Róbert FEBS Lett Research Letters Plant growth flexibly adapts to environmental conditions, implying cross‐talk between environmental signalling and developmental regulation. Here, we show that the PIN auxin efflux carrier family possesses three highly conserved putative mitogen‐activated protein kinase (MAPK) sites adjacent to the phosphorylation sites of the well‐characterised AGC kinase PINOID, which regulates the polar localisation of PINs and directional auxin transport, thereby underpinning organ growth. The conserved sites of PIN1 are phosphorylated in vitro by two environmentally activated MAPKs, MPK4 and MPK6. In contrast to AGC kinases, MAPK‐mediated phosphorylation of PIN1 at adjacent sites leads to a partial loss of the plasma membrane localisation of PIN1. MAPK‐mediated modulation of PIN trafficking may participate in environmental adjustment of plant growth. John Wiley and Sons Inc. 2017-12-25 2018-01 /pmc/articles/PMC5814726/ /pubmed/29197077 http://dx.doi.org/10.1002/1873-3468.12929 Text en © 2017 The Authors. FEBS Letters published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Letters
Dory, Magdalena
Hatzimasoura, Elizabeth
Kállai, Brigitta M.
Nagy, Szilvia K.
Jäger, Katalin
Darula, Zsuzsanna
Nádai, Tímea V.
Mészáros, Tamás
López‐Juez, Enrique
Barnabás, Beáta
Palme, Klaus
Bögre, László
Ditengou, Franck A.
Dóczi, Róbert
Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants
title Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants
title_full Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants
title_fullStr Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants
title_full_unstemmed Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants
title_short Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants
title_sort coevolving mapk and pid phosphosites indicate an ancient environmental control of pin auxin transporters in land plants
topic Research Letters
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814726/
https://www.ncbi.nlm.nih.gov/pubmed/29197077
http://dx.doi.org/10.1002/1873-3468.12929
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