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Structure and mechanism of a bacterial t(6)A biosynthesis system
The universal N(6)-threonylcarbamoyladenosine (t(6)A) modification at position 37 of ANN-decoding tRNAs is central to translational fidelity. In bacteria, t(6)A biosynthesis is catalyzed by the proteins TsaB, TsaC/TsaC2, TsaD and TsaE. Despite intense research, the molecular mechanisms underlying t(...
Autores principales: | Luthra, Amit, Swinehart, William, Bayooz, Susan, Phan, Phuc, Stec, Boguslaw, Iwata-Reuyl, Dirk, Swairjo, Manal A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814804/ https://www.ncbi.nlm.nih.gov/pubmed/29309633 http://dx.doi.org/10.1093/nar/gkx1300 |
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