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Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase

The Saccharomyces cerevisiae Pif1 protein (ScPif1p) is the prototypical member of the Pif1 family of DNA helicases. ScPif1p is involved in the maintenance of mitochondrial, ribosomal and telomeric DNA and suppresses genome instability at G-quadruplex motifs. Here, we report the crystal structures of...

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Detalles Bibliográficos
Autores principales:	Lu, Ke-Yu, Chen, Wei-Fei, Rety, Stephane, Liu, Na-Nv, Wu, Wen-Qiang, Dai, Yang-Xue, Li, Dan, Ma, Hai-Yun, Dou, Shuo-Xing, Xi, Xu-Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814829/ https://www.ncbi.nlm.nih.gov/pubmed/29202194 http://dx.doi.org/10.1093/nar/gkx1217

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