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Investigation of the Stereoselective Synthesis of the Indane Dimer PH46A, a New Potential Anti-inflammatory Agent

[Image: see text] PH46A, belonging to a class of 1,2-Indane dimers, has been developed by our research group as a potential therapeutic agent for the treatment of inflammatory and autoimmune diseases. The initial synthetic route to PH46A gave a low overall yield, due in large part to the generation...

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Detalles Bibliográficos
Autores principales: Cumming, Graham R., Zhang, Tao, Scalabrino, Gaia, Frankish, Neil, Sheridan, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814955/
https://www.ncbi.nlm.nih.gov/pubmed/29472755
http://dx.doi.org/10.1021/acs.oprd.7b00258