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Investigation of the Stereoselective Synthesis of the Indane Dimer PH46A, a New Potential Anti-inflammatory Agent
[Image: see text] PH46A, belonging to a class of 1,2-Indane dimers, has been developed by our research group as a potential therapeutic agent for the treatment of inflammatory and autoimmune diseases. The initial synthetic route to PH46A gave a low overall yield, due in large part to the generation...
Autores principales: | Cumming, Graham R., Zhang, Tao, Scalabrino, Gaia, Frankish, Neil, Sheridan, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814955/ https://www.ncbi.nlm.nih.gov/pubmed/29472755 http://dx.doi.org/10.1021/acs.oprd.7b00258 |
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