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La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region
Cell growth is a complex process shaped by extensive and coordinated changes in gene expression. Among these is the tightly regulated translation of a family of growth-related mRNAs defined by a 5′ terminal oligopyrimidine (TOP) motif. TOP mRNA translation is partly controlled via the eukaryotic ini...
Autores principales: | Philippe, Lucas, Vasseur, Jean-Jacques, Debart, Françoise, Thoreen, Carson C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814973/ https://www.ncbi.nlm.nih.gov/pubmed/29244122 http://dx.doi.org/10.1093/nar/gkx1237 |
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