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Jointly aligning a group of DNA reads improves accuracy of identifying large deletions
Performing sequence alignment to identify structural variants, such as large deletions, from genome sequencing data is a fundamental task, but current methods are far from perfect. The current practice is to independently align each DNA read to a reference genome. We show that the propensity of geno...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815140/ https://www.ncbi.nlm.nih.gov/pubmed/29182778 http://dx.doi.org/10.1093/nar/gkx1175 |