Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species

BACKGROUND: Mammalian species exhibit a wide range of lifespans. To date, a robust and dynamic molecular readout of these lifespan differences has not yet been identified. Recent studies have established the existence of ageing-associated differentially methylated positions (aDMPs) in human and mous...

Descripción completa

Detalles Bibliográficos
Autores principales: Lowe, Robert, Barton, Carl, Jenkins, Christopher A., Ernst, Christina, Forman, Oliver, Fernandez-Twinn, Denise S., Bock, Christoph, Rossiter, Stephen J., Faulkes, Chris G., Ozanne, Susan E., Walter, Lutz, Odom, Duncan T., Mellersh, Cathryn, Rakyan, Vardhman K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815211/
https://www.ncbi.nlm.nih.gov/pubmed/29452591
http://dx.doi.org/10.1186/s13059-018-1397-1

Ejemplares similares

Ejemplares similares