Cloxacillin induced agranulocytosis: A rare adverse event of a commonly used antibiotic

Cloxacillin, a semisynthetic penicillin is a potent inhibitor of most penicillinase-producing Staphylococci. Use of high doses of Cloxacillin for 6 weeks is recommended for the treatment of infective endocarditis caused by methicillin-susceptible Staphylococcus aureus (MSSA). Here, we report a case...

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Detalles Bibliográficos
Autores principales: Mani, Selvin Sundar Raj, Iyyadurai, Ramya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815267/
https://www.ncbi.nlm.nih.gov/pubmed/28786715
http://dx.doi.org/10.1177/0394632017724320
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author Mani, Selvin Sundar Raj
Iyyadurai, Ramya
author_facet Mani, Selvin Sundar Raj
Iyyadurai, Ramya
author_sort Mani, Selvin Sundar Raj
collection PubMed
description Cloxacillin, a semisynthetic penicillin is a potent inhibitor of most penicillinase-producing Staphylococci. Use of high doses of Cloxacillin for 6 weeks is recommended for the treatment of infective endocarditis caused by methicillin-susceptible Staphylococcus aureus (MSSA). Here, we report a case of Cloxacillin-induced agranulocytosis in a patient treated for MSSA native tricuspid valve endocarditis, which was resolved after discontinuation of the antibiotic. This case report highlights a rare adverse event of a commonly used antibiotic.
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spelling pubmed-58152672018-02-28 Cloxacillin induced agranulocytosis: A rare adverse event of a commonly used antibiotic Mani, Selvin Sundar Raj Iyyadurai, Ramya Int J Immunopathol Pharmacol Case Report Cloxacillin, a semisynthetic penicillin is a potent inhibitor of most penicillinase-producing Staphylococci. Use of high doses of Cloxacillin for 6 weeks is recommended for the treatment of infective endocarditis caused by methicillin-susceptible Staphylococcus aureus (MSSA). Here, we report a case of Cloxacillin-induced agranulocytosis in a patient treated for MSSA native tricuspid valve endocarditis, which was resolved after discontinuation of the antibiotic. This case report highlights a rare adverse event of a commonly used antibiotic. SAGE Publications 2017-08-08 2017-09 /pmc/articles/PMC5815267/ /pubmed/28786715 http://dx.doi.org/10.1177/0394632017724320 Text en © The Author(s) 2017 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Mani, Selvin Sundar Raj
Iyyadurai, Ramya
Cloxacillin induced agranulocytosis: A rare adverse event of a commonly used antibiotic
title Cloxacillin induced agranulocytosis: A rare adverse event of a commonly used antibiotic
title_full Cloxacillin induced agranulocytosis: A rare adverse event of a commonly used antibiotic
title_fullStr Cloxacillin induced agranulocytosis: A rare adverse event of a commonly used antibiotic
title_full_unstemmed Cloxacillin induced agranulocytosis: A rare adverse event of a commonly used antibiotic
title_short Cloxacillin induced agranulocytosis: A rare adverse event of a commonly used antibiotic
title_sort cloxacillin induced agranulocytosis: a rare adverse event of a commonly used antibiotic
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815267/
https://www.ncbi.nlm.nih.gov/pubmed/28786715
http://dx.doi.org/10.1177/0394632017724320
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