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Continuous-flow retro-Diels–Alder reaction: an efficient method for the preparation of pyrimidinone derivatives

The syntheses of various pyrimidinones as potentially bioactive products by means of the highly controlled continuous-flow retro-Diels–Alder reaction of condensed pyrimidinone derivatives are presented. Noteworthy, the use of this approach allowed us to rapidly screen a selection of conditions and q...

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Detalles Bibliográficos
Autores principales: Nekkaa, Imane, Palkó, Márta, Mándity, István M, Fülöp, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815275/
https://www.ncbi.nlm.nih.gov/pubmed/29507637
http://dx.doi.org/10.3762/bjoc.14.20