Antitumor effect of triptolide in T-cell lymphoblastic lymphoma by inhibiting cell viability, invasion, and epithelial–mesenchymal transition via regulating the PI3K/AKT/mTOR pathway

INTRODUCTION: T-cell lymphoblastic lymphoma (T-LBL) is a widely disseminated disease worldwide. Triptolide (TPL) is purified from Chinese herb and displays anti-inflammatory, anti-fertility, anti-tumor and immunosuppressive effects. MATERIALS AND METHODS: Here, in vitro and in vivo experiments were...

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Detalles Bibliográficos
Autores principales: Huang, Yan, Wu, Sun, Zhang, Yuan, Wang, Lihua, Guo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815473/
https://www.ncbi.nlm.nih.gov/pubmed/29483777
http://dx.doi.org/10.2147/OTT.S149788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815473/
https://www.ncbi.nlm.nih.gov/pubmed/29483777
http://dx.doi.org/10.2147/OTT.S149788

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