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Antitumor effect of triptolide in T-cell lymphoblastic lymphoma by inhibiting cell viability, invasion, and epithelial–mesenchymal transition via regulating the PI3K/AKT/mTOR pathway
INTRODUCTION: T-cell lymphoblastic lymphoma (T-LBL) is a widely disseminated disease worldwide. Triptolide (TPL) is purified from Chinese herb and displays anti-inflammatory, anti-fertility, anti-tumor and immunosuppressive effects. MATERIALS AND METHODS: Here, in vitro and in vivo experiments were...
Autores principales: | Huang, Yan, Wu, Sun, Zhang, Yuan, Wang, Lihua, Guo, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815473/ https://www.ncbi.nlm.nih.gov/pubmed/29483777 http://dx.doi.org/10.2147/OTT.S149788 |
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