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High-dose amikacin for achieving serum target levels in critically ill elderly patients

INTRODUCTION: To achieve target concentrations, the application of higher-than-standard doses of amikacin is proposed for the treatment of sepsis due to an increase in volume of distribution and clearance, but little data are available on aminoglycoside administration in critically ill elderly patie...

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Detalles Bibliográficos
Autores principales: Sadeghi, Kourosh, Hamishehkar, Hadi, Najmeddin, Farhad, Ahmadi, Arezoo, Hazrati, Ebrahim, Honarmand, Hooshyar, Mojtahedzadeh, Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815475/
https://www.ncbi.nlm.nih.gov/pubmed/29483780
http://dx.doi.org/10.2147/IDR.S150839