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Redox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol

Brusatol (Bru) exhibits promising anticancer effects, with both proliferation inhibition and chemoresistance amelioration activity. However, the poor solubility and insufficient intracellular delivery of Bru greatly restrict its application. Herein, to simultaneously utilize the advantages of Pluron...

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Detalles Bibliográficos
Autores principales: Zhang, Jinming, Fang, Xiaobin, Li, Zeyong, Chan, Hon Fai, Lin, Zhixiu, Wang, Yitao, Chen, Meiwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815479/
https://www.ncbi.nlm.nih.gov/pubmed/29491708
http://dx.doi.org/10.2147/IJN.S130696