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Functional intercalated nanocomposites with chitosan-glutathione-glycylsarcosine and layered double hydroxides for topical ocular drug delivery

BACKGROUND: To enhance ocular bioavailability, the traditional strategies have focused on prolonging precorneal retention and improving corneal permeability by nano-carriers with positive charge, thiolated polymer, absorption enhancer and so on. Glycylsarcosine (GS) as an active target ligand of the...

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Detalles Bibliográficos
Autores principales: Xu, Tingting, Xu, Xiaoyue, Gu, Yan, Fang, Lei, Cao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815481/
https://www.ncbi.nlm.nih.gov/pubmed/29491707
http://dx.doi.org/10.2147/IJN.S148104