αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis

BACKGROUND AND AIMS: The αEβ7 integrin is crucial for retention of T lymphocytes at mucosal surfaces through its interaction with E-cadherin. Pathogenic or protective functions of these cells during human intestinal inflammation, such as ulcerative colitis [UC], have not previously been defined, wit...

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Detalles Bibliográficos
Autores principales: Lamb, Christopher A., Mansfield, John C., Tew, Gaik W., Gibbons, Deena, Long, Anna K., Irving, Peter, Diehl, Lauri, Eastham-Anderson, Jeff, Price, Maria B., O’Boyle, Graeme, Jones, David E. J., O’Byrne, Sharon, Hayday, Adrian, Keir, Mary E., Egen, Jackson G., Kirby, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815571/
https://www.ncbi.nlm.nih.gov/pubmed/28453768
http://dx.doi.org/10.1093/ecco-jcc/jjw189

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