Association of an intact E2 gene with higher HPV viral load, higher viral oncogene expression, and improved clinical outcome in HPV16 positive head and neck squamous cell carcinoma

To assess the relationship of E2 gene disruption with viral gene expression and clinical outcome in human papillomavirus (HPV) positive head and neck squamous cell carcinoma, we evaluated 31 oropharyngeal and 17 non-oropharyngeal HPV16 positive carcinomas using two PCR-based methods to test for disr...

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Detalles Bibliográficos
Autores principales: Anayannis, Nicole V., Schlecht, Nicolas F., Ben-Dayan, Miriam, Smith, Richard V., Belbin, Thomas J., Ow, Thomas J., Blakaj, Duk M., Burk, Robert D., Leonard, Sarah M., Woodman, Ciaran B., Parish, Joanna L., Prystowsky, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815588/
https://www.ncbi.nlm.nih.gov/pubmed/29451891
http://dx.doi.org/10.1371/journal.pone.0191581

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