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Development of encorafenib for BRAF-mutated advanced melanoma

PURPOSE OF REVIEW: To describe the pharmacological properties, preclinical and clinical data of the novel V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF)-inhibitor encorafenib (LGX818) and to compare these with established BRAF-inhibitors in the treatment of locally advanced or metastatic melan...

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Detalles Bibliográficos
Autores principales:	Koelblinger, Peter, Thuerigen, Olaf, Dummer, Reinhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2018
Materias:	MELANOMA AND OTHER SKIN NEOPLASMS: Edited by Reinhard Dummer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815646/ https://www.ncbi.nlm.nih.gov/pubmed/29356698 http://dx.doi.org/10.1097/CCO.0000000000000426

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