Case report: One case of primary AL amyloidosis repeatedly misdiagnosed as scleroderma

INTRODUCTION: Amyloid light chain (AL) results from the deposition of immunoglobulin light chain fragments, and can affect multiple organs/systems. Our patient was diagnosed as scleroderma repeatedly because of extensive skin thickening and hardening, but the treatment was not effective. We did exte...

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Detalles Bibliográficos
Autores principales: Sun, Linge, Zhang, Lei, Hu, Wenlu, Li, Tian-Fang, Liu, Shengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
4800
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815680/
https://www.ncbi.nlm.nih.gov/pubmed/29390268
http://dx.doi.org/10.1097/MD.0000000000008771
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author Sun, Linge
Zhang, Lei
Hu, Wenlu
Li, Tian-Fang
Liu, Shengyun
author_facet Sun, Linge
Zhang, Lei
Hu, Wenlu
Li, Tian-Fang
Liu, Shengyun
author_sort Sun, Linge
collection PubMed
description INTRODUCTION: Amyloid light chain (AL) results from the deposition of immunoglobulin light chain fragments, and can affect multiple organs/systems. Our patient was diagnosed as scleroderma repeatedly because of extensive skin thickening and hardening, but the treatment was not effective. We did extensive laboratory examinations including serum/urine protein electrophoresis and flow cytometry assay of bone marrow aspiration. CONCLUSION: A diagnosis of primary AL amyloidosis was established.
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spelling pubmed-58156802018-02-28 Case report: One case of primary AL amyloidosis repeatedly misdiagnosed as scleroderma Sun, Linge Zhang, Lei Hu, Wenlu Li, Tian-Fang Liu, Shengyun Medicine (Baltimore) 4800 INTRODUCTION: Amyloid light chain (AL) results from the deposition of immunoglobulin light chain fragments, and can affect multiple organs/systems. Our patient was diagnosed as scleroderma repeatedly because of extensive skin thickening and hardening, but the treatment was not effective. We did extensive laboratory examinations including serum/urine protein electrophoresis and flow cytometry assay of bone marrow aspiration. CONCLUSION: A diagnosis of primary AL amyloidosis was established. Wolters Kluwer Health 2017-12-15 /pmc/articles/PMC5815680/ /pubmed/29390268 http://dx.doi.org/10.1097/MD.0000000000008771 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 4800
Sun, Linge
Zhang, Lei
Hu, Wenlu
Li, Tian-Fang
Liu, Shengyun
Case report: One case of primary AL amyloidosis repeatedly misdiagnosed as scleroderma
title Case report: One case of primary AL amyloidosis repeatedly misdiagnosed as scleroderma
title_full Case report: One case of primary AL amyloidosis repeatedly misdiagnosed as scleroderma
title_fullStr Case report: One case of primary AL amyloidosis repeatedly misdiagnosed as scleroderma
title_full_unstemmed Case report: One case of primary AL amyloidosis repeatedly misdiagnosed as scleroderma
title_short Case report: One case of primary AL amyloidosis repeatedly misdiagnosed as scleroderma
title_sort case report: one case of primary al amyloidosis repeatedly misdiagnosed as scleroderma
topic 4800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815680/
https://www.ncbi.nlm.nih.gov/pubmed/29390268
http://dx.doi.org/10.1097/MD.0000000000008771
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