MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling

Rett Syndrome (RTT) is an X-linked, neurodevelopmental disorder caused primarily by mutations in the Methyl-CpG-binding protein 2 (MECP2) gene, which encodes a multifunctional epigenetic regulator with known links to a wide spectrum of neuropsychiatric disorders. While postnatal functions of MeCP2 h...

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Detalles Bibliográficos
Autores principales: Mellios, Nikolaos, Feldman, Danielle A., Sheridan, Steven D., Ip, Jacque P.K., Kwok, Showming, Amoah, Stephen K., Rosen, Bess, Rodriguez, Brian A., Crawford, Benjamin, Swaminathan, Radha, Chou, Stephanie, Li, Yun, Ziats, Mark, Ernst, Carl, Jaenisch, Rudolf, Haggarty, Stephen J., Sur, Mriganka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815944/
https://www.ncbi.nlm.nih.gov/pubmed/28439102
http://dx.doi.org/10.1038/mp.2017.86

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