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Hepatitis B Virus-Specific CD8+ T Cells Maintain Functional Exhaustion after Antigen Reexposure in an Acute Activation Immune Environment

Chronic hepatitis B virus (HBV) infection is characterized by the presence of functionally exhausted HBV-specific CD8+ T cells. To characterize the possible residual effector ability of these cells, we reexposed CD8+ T cells from chronically HBV replicating mice to HBV antigens in an acute activatio...

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Detalles Bibliográficos
Autores principales:	Wang, Qin, Pan, Wen, Liu, Yanan, Luo, Jinzhuo, Zhu, Dan, Lu, Yinping, Feng, Xuemei, Yang, Xuecheng, Dittmer, Ulf, Lu, Mengji, Yang, Dongliang, Liu, Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816053/ https://www.ncbi.nlm.nih.gov/pubmed/29483916 http://dx.doi.org/10.3389/fimmu.2018.00219

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