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LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to regulate the Warburg effect

The oncoprotein c-Myc plays an important role in regulating glycolysis under normoxia; yet, in cancer cells, HIF1α, which is essential for driving glycolysis under hypoxia, is often up-regulated even in the presence of oxygen. The relationship between these two major regulators of the Warburg effect...

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Detalles Bibliográficos
Autores principales:	Xiang, Shaoxun, Gu, Hao, Jin, Lei, Thorne, Rick F., Zhang, Xu Dong, Wu, Mian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816142/ https://www.ncbi.nlm.nih.gov/pubmed/29378948 http://dx.doi.org/10.1073/pnas.1711257115

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