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RNA force field with accuracy comparable to state-of-the-art protein force fields
Molecular dynamics (MD) simulation has become a powerful tool for characterizing at an atomic level of detail the conformational changes undergone by proteins. The application of such simulations to RNA structures, however, has proven more challenging, due in large part to the fact that the physical...
Autores principales: | Tan, Dazhi, Piana, Stefano, Dirks, Robert M., Shaw, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816156/ https://www.ncbi.nlm.nih.gov/pubmed/29378935 http://dx.doi.org/10.1073/pnas.1713027115 |
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