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Locally Advanced Basal Cell Carcinoma with Intraocular Invasion

We present a 103 - year - old patient, with duration of complaints of about ten years. The initial complaint had been presented as a small nodule, located on the eyebrow, which subsequently ulcerated and encompassed larger regions of the upper and lower eyelids. For the past three years, the patient...

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Autores principales: Tchernev, Georgi, Lotti, Torello, Lozev, Ilia, Maximov, Georgi Konstantinov, Wollina, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816281/
https://www.ncbi.nlm.nih.gov/pubmed/29484007
http://dx.doi.org/10.3889/oamjms.2018.012
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author Tchernev, Georgi
Lotti, Torello
Lozev, Ilia
Maximov, Georgi Konstantinov
Wollina, Uwe
author_facet Tchernev, Georgi
Lotti, Torello
Lozev, Ilia
Maximov, Georgi Konstantinov
Wollina, Uwe
author_sort Tchernev, Georgi
collection PubMed
description We present a 103 - year - old patient, with duration of complaints of about ten years. The initial complaint had been presented as a small nodule, located on the eyebrow, which subsequently ulcerated and encompassed larger regions of the upper and lower eyelids. For the past three years, the patient also had complaints of a worsening of his vision, without seeking for medical help. Within the dermatological examination, an intraocular and periocular localised tumour was established, characterised by a raised peripheral edge and central ulceration. More careful examination revealed that the bulb was fully consumed. The patient refused further diagnosis and treatment. Advanced basal cell carcinomas with intraocular invasion are rare in general. If the patient refuses surgery, radiotherapy and systemic therapy with modern medications such as Vismodegib or Sonidegib are available as treatment options.
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spelling pubmed-58162812018-02-26 Locally Advanced Basal Cell Carcinoma with Intraocular Invasion Tchernev, Georgi Lotti, Torello Lozev, Ilia Maximov, Georgi Konstantinov Wollina, Uwe Open Access Maced J Med Sci Case Report We present a 103 - year - old patient, with duration of complaints of about ten years. The initial complaint had been presented as a small nodule, located on the eyebrow, which subsequently ulcerated and encompassed larger regions of the upper and lower eyelids. For the past three years, the patient also had complaints of a worsening of his vision, without seeking for medical help. Within the dermatological examination, an intraocular and periocular localised tumour was established, characterised by a raised peripheral edge and central ulceration. More careful examination revealed that the bulb was fully consumed. The patient refused further diagnosis and treatment. Advanced basal cell carcinomas with intraocular invasion are rare in general. If the patient refuses surgery, radiotherapy and systemic therapy with modern medications such as Vismodegib or Sonidegib are available as treatment options. Republic of Macedonia 2018-01-13 /pmc/articles/PMC5816281/ /pubmed/29484007 http://dx.doi.org/10.3889/oamjms.2018.012 Text en Copyright: © 2018 Georgi Tchernev, Torello Lotti, Ilia Lozev, Georgi Konstantinov Maximov, Uwe Wollina. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Case Report
Tchernev, Georgi
Lotti, Torello
Lozev, Ilia
Maximov, Georgi Konstantinov
Wollina, Uwe
Locally Advanced Basal Cell Carcinoma with Intraocular Invasion
title Locally Advanced Basal Cell Carcinoma with Intraocular Invasion
title_full Locally Advanced Basal Cell Carcinoma with Intraocular Invasion
title_fullStr Locally Advanced Basal Cell Carcinoma with Intraocular Invasion
title_full_unstemmed Locally Advanced Basal Cell Carcinoma with Intraocular Invasion
title_short Locally Advanced Basal Cell Carcinoma with Intraocular Invasion
title_sort locally advanced basal cell carcinoma with intraocular invasion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816281/
https://www.ncbi.nlm.nih.gov/pubmed/29484007
http://dx.doi.org/10.3889/oamjms.2018.012
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