Cargando…
Locally Advanced Basal Cell Carcinoma with Intraocular Invasion
We present a 103 - year - old patient, with duration of complaints of about ten years. The initial complaint had been presented as a small nodule, located on the eyebrow, which subsequently ulcerated and encompassed larger regions of the upper and lower eyelids. For the past three years, the patient...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Republic of Macedonia
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816281/ https://www.ncbi.nlm.nih.gov/pubmed/29484007 http://dx.doi.org/10.3889/oamjms.2018.012 |
_version_ | 1783300638824726528 |
---|---|
author | Tchernev, Georgi Lotti, Torello Lozev, Ilia Maximov, Georgi Konstantinov Wollina, Uwe |
author_facet | Tchernev, Georgi Lotti, Torello Lozev, Ilia Maximov, Georgi Konstantinov Wollina, Uwe |
author_sort | Tchernev, Georgi |
collection | PubMed |
description | We present a 103 - year - old patient, with duration of complaints of about ten years. The initial complaint had been presented as a small nodule, located on the eyebrow, which subsequently ulcerated and encompassed larger regions of the upper and lower eyelids. For the past three years, the patient also had complaints of a worsening of his vision, without seeking for medical help. Within the dermatological examination, an intraocular and periocular localised tumour was established, characterised by a raised peripheral edge and central ulceration. More careful examination revealed that the bulb was fully consumed. The patient refused further diagnosis and treatment. Advanced basal cell carcinomas with intraocular invasion are rare in general. If the patient refuses surgery, radiotherapy and systemic therapy with modern medications such as Vismodegib or Sonidegib are available as treatment options. |
format | Online Article Text |
id | pubmed-5816281 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Republic of Macedonia |
record_format | MEDLINE/PubMed |
spelling | pubmed-58162812018-02-26 Locally Advanced Basal Cell Carcinoma with Intraocular Invasion Tchernev, Georgi Lotti, Torello Lozev, Ilia Maximov, Georgi Konstantinov Wollina, Uwe Open Access Maced J Med Sci Case Report We present a 103 - year - old patient, with duration of complaints of about ten years. The initial complaint had been presented as a small nodule, located on the eyebrow, which subsequently ulcerated and encompassed larger regions of the upper and lower eyelids. For the past three years, the patient also had complaints of a worsening of his vision, without seeking for medical help. Within the dermatological examination, an intraocular and periocular localised tumour was established, characterised by a raised peripheral edge and central ulceration. More careful examination revealed that the bulb was fully consumed. The patient refused further diagnosis and treatment. Advanced basal cell carcinomas with intraocular invasion are rare in general. If the patient refuses surgery, radiotherapy and systemic therapy with modern medications such as Vismodegib or Sonidegib are available as treatment options. Republic of Macedonia 2018-01-13 /pmc/articles/PMC5816281/ /pubmed/29484007 http://dx.doi.org/10.3889/oamjms.2018.012 Text en Copyright: © 2018 Georgi Tchernev, Torello Lotti, Ilia Lozev, Georgi Konstantinov Maximov, Uwe Wollina. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). |
spellingShingle | Case Report Tchernev, Georgi Lotti, Torello Lozev, Ilia Maximov, Georgi Konstantinov Wollina, Uwe Locally Advanced Basal Cell Carcinoma with Intraocular Invasion |
title | Locally Advanced Basal Cell Carcinoma with Intraocular Invasion |
title_full | Locally Advanced Basal Cell Carcinoma with Intraocular Invasion |
title_fullStr | Locally Advanced Basal Cell Carcinoma with Intraocular Invasion |
title_full_unstemmed | Locally Advanced Basal Cell Carcinoma with Intraocular Invasion |
title_short | Locally Advanced Basal Cell Carcinoma with Intraocular Invasion |
title_sort | locally advanced basal cell carcinoma with intraocular invasion |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816281/ https://www.ncbi.nlm.nih.gov/pubmed/29484007 http://dx.doi.org/10.3889/oamjms.2018.012 |
work_keys_str_mv | AT tchernevgeorgi locallyadvancedbasalcellcarcinomawithintraocularinvasion AT lottitorello locallyadvancedbasalcellcarcinomawithintraocularinvasion AT lozevilia locallyadvancedbasalcellcarcinomawithintraocularinvasion AT maximovgeorgikonstantinov locallyadvancedbasalcellcarcinomawithintraocularinvasion AT wollinauwe locallyadvancedbasalcellcarcinomawithintraocularinvasion |