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Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype

BACKGROUND: During embryonic development Wnt family members and bone morphogenetic proteins (BMPs) cooperatively induce epithelial-mesenchymal transition (EMT) in the neural crest. Wnt and BMPs are reactivated during malignant transformation in melanoma. We previously demonstrated that the BMP-antag...

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Detalles Bibliográficos
Autores principales:	Sinnberg, Tobias, Levesque, Mitchell P., Krochmann, Jelena, Cheng, Phil F., Ikenberg, Kristian, Meraz-Torres, Francisco, Niessner, Heike, Garbe, Claus, Busch, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816360/ https://www.ncbi.nlm.nih.gov/pubmed/29454361 http://dx.doi.org/10.1186/s12943-018-0773-5

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