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Participation of Arachidonic Acid Metabolism in the Aortic Aneurysm Formation in Patients with Marfan Syndrome

Marfan syndrome (MFS) is a pleiotropic genetic disease involving the cardiovascular system where a fibrillin-1 mutation is present. This mutation is associated with accelerated activation of transforming growth factor β (TGFβ1) which contributes to the formation of aneurysms in the root of the aorta...

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Detalles Bibliográficos
Autores principales: Soto, María E., Guarner-Lans, Verónica, Herrera-Morales, Karla Y., Pérez-Torres, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816394/
https://www.ncbi.nlm.nih.gov/pubmed/29483877
http://dx.doi.org/10.3389/fphys.2018.00077

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