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Alternative splicing of ALCAM enables tunable regulation of cell-cell adhesion through differential proteolysis

While many adhesion receptors are known to influence tumor progression, the mechanisms by which they dynamically regulate cell-cell adhesion remain elusive. We previously identified Activated Leukocyte Cell Adhesion Molecule (ALCAM) as a clinically relevant driver of metastasis and hypothesized that...

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Detalles Bibliográficos
Autores principales: Hebron, Katie E., Li, Elizabeth Y., Arnold Egloff, Shanna A., von Lersner, Ariana K., Taylor, Chase, Houkes, Joep, Flaherty, David K., Eskaros, Adel, Stricker, Thomas P., Zijlstra, Andries
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816644/
https://www.ncbi.nlm.nih.gov/pubmed/29453336
http://dx.doi.org/10.1038/s41598-018-21467-x

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