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Alternative splicing of ALCAM enables tunable regulation of cell-cell adhesion through differential proteolysis
While many adhesion receptors are known to influence tumor progression, the mechanisms by which they dynamically regulate cell-cell adhesion remain elusive. We previously identified Activated Leukocyte Cell Adhesion Molecule (ALCAM) as a clinically relevant driver of metastasis and hypothesized that...
Autores principales: | Hebron, Katie E., Li, Elizabeth Y., Arnold Egloff, Shanna A., von Lersner, Ariana K., Taylor, Chase, Houkes, Joep, Flaherty, David K., Eskaros, Adel, Stricker, Thomas P., Zijlstra, Andries |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816644/ https://www.ncbi.nlm.nih.gov/pubmed/29453336 http://dx.doi.org/10.1038/s41598-018-21467-x |
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